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diagnosis management differential pulmonary associations comparison dermatology lupus syndrome abscess activation antibodies antimda5 antimda5dm antinxp2 antinxp2dm autoantibodies autoimmune calcium causes
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung ... DM/PM : dermatomyositis ... rheumatoid arthritis SLE ... ConnectiveTissueDiseases #ILD ... #Pulmonary #Rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- Drug-induced SLE ... Anti-Jo-1 - Polymyositis ... / Dermatomyositis ... #diagnosis #table ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, dermatomyositis ... Non-autoimmune rheumatologic ... • Acute lupus pneumonitis ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
severity of the disease ... and ILD • Liver ... anti-NXP2 Abs Lung ... Phenotype 1 ... #rheumatology #
The idiopathic interstitial pneumonias (IIPs) comprise a heterogenous group of disorders. They represent fundamental responses of
idiopathic interstitial pneumonias ... responses of the lung ... ' per se. ... listed in the table ... IdiopathicInterstitialPneumonia #ILD
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Abscess Pathophysiology ... : 1. ... Pneumonitis 3. ... antibiotics once stable ... shows a small, stable
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Prognosis: Usually mild ... Evolution: Chronic disease ... #comparison #table ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
highly inflammatory disease ... -1 and IL-6, leading ... rash) • Heart, lung ... erythematosus [SLE ... #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
had more severe disease ... Non-small-cell lung ... : • ILD was diagnosed ... Prednisone at 1 ... diagnosis #management #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... overlaps with RA, SLE ... • Interstitial Pneumonitis ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology
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