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diagnosis management differential pulmonary comparison diseases associations causes cppd dermatology hematology abscess activation antibodies antimda5 antimda5dm antinxp2 antinxp2dm autoantibodies autoimmune
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
Diseases (ILD) ... , Polymyositis-dermatomyositis ... disease (RB-ILD ... Churg Strauss syndrome ... #Diseases #ILD
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung ... DM/PM : dermatomyositis ... PSS: Sjogren syndrome ... ConnectiveTissueDiseases #ILD ... #Pulmonary #Rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Drug-induced SLE Anti-Jo-1 ... Polymyositis / Dermatomyositis ... La) - Sjogren's syndrome ... #diagnosis #table ... #rheumatology #
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
severity of the disease ... and ILD • Liver ... anti-NXP2 Abs Lung ... Phenotype 1 ... #rheumatology #
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Abscess Pathophysiology ... : 1. ... Pneumonitis 3. ... antibiotics once stable ... shows a small, stable
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, dermatomyositis ... Non-autoimmune rheumatologic ... • Acute lupus pneumonitis ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
to Eosinophilic Lung ... Diseases • Acute ... Eosinophilic Pneumonia (< 1 ... Hypereosinophilic Syndrome ... diagnosis #comparison #table
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... highly inflammatory disease ... -1 and IL-6, leading ... rash) • Heart, lung ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... Antinuclear antibodies ≥ 1: ... • Interstitial Pneumonitis ... MALT Lymphoma • Lung ... #Rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... ), dermato-rheumatologic ... Ab • Anti-Jo-1 ... enzymes • Anti-Jo-1 ... Myositis #Myopathy #rheumatology
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