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diagnosis antibody antinuclear cytoplasmic testing aggregometry arthritis autoimmune congestion disorders erythematosus fever grades grading hematology hemepath infections instructions intermittent joint
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
SLE, SjS, CTD-ILD ... phenomenon - EJ, Jo-1, ... ARUPConsult @ARUPLabs #ANA ... #differential # ... diagnosis #rheumatology
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
similar aggregation pattern ... cytometry — GP Ilb ... agonists • This pattern ... either severe Type 1 ... or Type 3) — differentiate
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - ... Differential Diagnosis ... fever • Hyper-IgD ... syndrome • Tumor ... #Differential #
Venous Excess Ultrasound (VExUS) - Fluid Overload and Venous Congestion Assessment Step 1: IVC Diameter: If >2cm,
Venous Excess Ultrasound ... Assessment Step 1: ... IVC < 2cm Grade 1 ... (Mild congestion ... VExUS #diagnosis #pocus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... • Acute lupus pneumonitis ... titers > 1:80 ... Ro/La, anti-Jo-1,
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... • Is there a pattern ... lasting > 30 mins - 1 ... asymmetric pattern ... #Joint #pain #Differential
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Testing Cytoplasmic Patterns ... SLE, SjS, CTD-ILD ... phenomenon • EJ, Jo-1, ... #differential # ... diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Anti-MDA5 (RP-ILD ... Ab • Anti-Jo-1 ... pattern of muscle ... #differential #
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