31 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
hemolysis, deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD ... Kawasaki, Nephrotic syndrome ... : Chronic infections
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... diagnosis: 70 years old ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... #hematology #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
F • 3 peaks: 1) ... Clinical Presentation ... Idiopathic • Infections ... Treatment: ... #oncology #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
-1 and IL-6, leading ... SLE], AOSD) • Infection ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Rheumatology
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Acute Retroviral Syndrome ... Acute Retroviral Syndrome ... enzymes ↑ • Mild ... anemia • Thrombocytopenia ... antibody test) Treatment
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... and 1:50,000 patients ... to 8 years Clinical ... autoimmune hemolytic anemia ... : • Nephrotic syndrome
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... 5) Symptoms of anemia ... Infection due to ... marrow failure with anemia ... Leukemia #oncology #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Antibodies: 1. ... Cold Agglutinin Syndrome ... Clinical Presentation ... • Symptoms of anemia ... #hematology #diagnosis
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1- ... response preceding infection ... • Weakness: mild ... Guillain-Barre Clinical ... main variants: (1)
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... causes such as infectious ... and lower jaw Treatment ... -1 inhibitors, IL ... #Rheumatology #