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diagnosis management hematology lupus sle activation arthritis comparison dermatology differential disease erythematosus hemeonc hemophagocytic hlh incomplete kawasaki lymphohistiocytosis macrophage mas
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Prognosis: Usually mild ... • Clinical Manifestations ... Lupusreference #druginduced ... comparison #table #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Glucocorticoids, IL ... Differential #Diagnosis #Algorithm
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
cytokines, such as IL ... -1 and IL-6, leading ... Increased soluble IL ... Treatment: • Corticosteroids ... #Rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... Prognosis: Usually mild ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology ... #diagnosis #treatment
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
and lower jaw Treatment ... efficacious include IL ... -1 inhibitors, IL ... inhibitors, and IL ... #Rheumatology #
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
AM stiffness, >1 ... Ultrasound Diagnosis: CLINICAL ... exam and imaging Treatment ... Certolizumab, Golimumab), IL ... diagnosis #management #rheumatology
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
Kawasaki Disease 1. ... Infants ≤6 months old ... if they have no clinical ... Albumin ≤3.0 g/dL ... echo is positive, treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Clinical Features ... • Acute lupus pneumonitis ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... salivary ducts Clinical ... • Interstitial Pneumonitis ... Adenocarcinoma Treatment ... #Rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
dysfunction. 1. ... Clinical Presentation ... ., IFN-γ, TNF, IL ... Elevated soluble IL ... Diagnosis #Management #Hematology
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