5 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Testing - Nuclear ... SLE, SjS, CTD-ILD ... phenomenon - EJ, Jo-1, ... #differential # ... diagnosis #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody ... SLE, SjS, CTD-ILD ... phenomenon • EJ, Jo-1, ... #Patterns #differential ... #diagnosis #rheumatology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
similar aggregation pattern ... cytometry — GP Ilb ... either severe Type 1 ... considered first-line testing ... Platelet #disorders #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... • Is there a pattern ... > 30 mins - 1 hour ... an asymmetric pattern ... #Joint #pain #Differential
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
levels • NXP-2 antibody ... Prednisone at 1 ... methylprednisolone 1 ... diagnosis #management #rheumatology ... #dermatology