10 results
diagnosis differential ana antinuclear cytoplasmic dermatomyositis management pain testing aggregometry antimda5 antimda5dm antinxp2 antinxp2dm arthritis autoimmune disorders erythematosus hematology hemepath
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... SLE, SjS, CTD-ILD ... phenomenon - EJ, Jo-1, ... #Antinuclear #Antibody ... differential #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... gangrenosum • IBD ... Antiphospholipid-antibody ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
• Is there a pattern ... lasting > 30 mins - 1 ... - Autoimmune Rheumatologic ... an asymmetric pattern ... Diagnosis #MSK #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
efficacious include IL ... -1 inhibitors, IL ... inhibitors, and IL ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... Testing Cytoplasmic Patterns ... SLE, SjS, CTD-ILD ... phenomenon • EJ, Jo-1, ... differential #diagnosis #rheumatology
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
similar aggregation pattern ... cytometry — GP Ilb ... agonists • This pattern ... either severe Type 1 ... Platelet #disorders #hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
interphalangeal joints ... increases and ILD ... Phenotype 1 ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Acute lupus pneumonitis ... Arthritis: • Joint ... arthropathy • 90% joints ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
interphalangeal joints ... levels • NXP-2 antibody ... Dermatomyositis: • ILD ... diagnosis #management #rheumatology ... #dermatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... ), dermato-rheumatologic ... Ab • Anti-Jo-1 ... Syndrome: Fever, joint ... slow onset and pattern
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