9 results
ILD of Known Cause - Differential Diagnosis
Exposure:
 • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis
 • Treatment Related:
ILD of Known Cause ... Hypersensitivity, Pneumonitis ... • Treatment Related ... #Diagnosis #interstitial ... lung #disease #pulmonary
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Drugs, Unknown cause ... Treatment: • ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Cryptogenic Organizing Pneumonia (COP)

Cryptogenic Organizing Pneumonia Overview:
 • Idiopathic form of organizing pneumonia
 • formerly BOOP
Unknown • 6-7 cases ... Organizing Pneumonia Treatment ... Pneumonia #COP #BOOP #pulmonary ... #ILD #diagnosis ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
) Treatment Primary ... steroids • In mild ... cases associated ... #Treatment #management ... #hematology
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
starting amiodarone treatment ... Exclude other causes ... Exclusion of other ILDs ... macrophages Treatment ... #diagnosis #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Prognosis: Usually mild ... Discontinuation of causal ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Pneumonitis (LIP ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome caused ... search for and treatment ... Treatment Approach ... #Hematology #HemeOnc
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Prognosis: Usually mild ... Discontinuation of causal ... DrugInduced #Lupus #DIL #rheumatology ... #diagnosis #treatment ... #management