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differentiation emergencies erythematosus gammopathy hemeonc lupus management mds mgus monoclonal myelodysplasia myelodysplastic oncologic rheumatology significance sle syndrome syndromes systemic undetermined
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Attempt if high risk ... : >3 symptoms, or ... Differentiation #Syndrome #APML ... #hematology #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... constitutional symptoms ... isotype (rarely IgD ... #Significance #hematology ... #diagnosis #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... • Acute lupus pneumonitis ... Induced Lupus: • Symptoms ... Thrombosis highest risk ... Erythematosus #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... carries a variable risk ... and reducing the risk ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... syndrome): - Hematologic ... mg/dL or > 25 % rise ... (~20 %) and APL ... #HemeOnc #Diagnosis
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