17 results
Podocytopathies - Differential Diagnosis Algorithm

No podocytopenia - EM shows minimal change disease
 • Minimal Change Nephropathy
Podocytopenia
• FSGS NOS Podocyte ... Podocytopathy #podocytes
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
Codocytes (Target ... #Blood #Smear #Codocytes
Several artifacts can cause significant and potentially misleading alterations to measured RBC parameters: 
1. Old samples
#TargetCells #Codocytes
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Nephrotic yndrome—podocyte ... 10 (eg direct podocyte ... damage) or 20 (podocyte
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
• Injury to podocytes
Pathogenesis of PLA2R-associated (primary) Membranous Nephropathy

Immune deposits  → Activate complement  → C5b-9 complex
C5b-9 complex → Podocyte
Glomerular Tuft on Electron Microscopy

This eyeSCANdy image shows acellular scanning EM of a normal glomerular tuft
removal of the podocytes
Glomerular Tuft on Electron Microscopy

This eyeSCANdy image shows acellular scanning EM of a normal glomerular tuft
removal of the podocytes
This image shows scanning EM of a proteinuric glomerulus with capillary loop showing widening and partial
interdigitating podocyte
Normal Glomerulus on Electron Microscopy
This eyeSCANdy image shows scanning EM of normal glomerulus showing glomerular capillary
interdigitating podocyte