31 results
The arrows point to blister cells. These cells are thought to be precursors of helmet cells.
thought to be precursors ... Clinical #Path #BloodSmear ... #Blood #Smear #
Elliptocyte - 
Note the shape of these appropriately named erythrocytes.
In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... Clinical #Path #BloodSmear ... #Blood #Smear #
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
metaplasia, pernicious anemia ... some hemolytic anemias ... Clinical #Path #BloodSmear ... #Blood #Smear #
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
peripheral blood smear ... iron deficiency anemia ... PeripheralBloodSmear #BloodSmear ... #Anemia #IronDeficiency
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... Megaloblastic Anemia ... Autoimmune hemolytic anemia ... cells: Sickle cell disease ... Peripheral #Blood #Smear
Nucleated red blood cells, aka normoblasts or erythroblasts, were released prematurely from the bone marrow in
maturation of red cell precursors ... #Path #Peds #BloodSmear ... #Blood #Smear #
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
with hemolytic anemias ... Clinical #Path #BloodSmear ... #Blood #Smear #
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Normochromic RBCs on Smear ... • Anemia of Chronic ... Disease • Marrow ... Spherocytes on Smear
Stomatocyte - The appearance of stomatocytes with their oval or rectangular central pallor has been compared
seen in liver disease ... Clinical #Path #BloodSmear ... #Blood #Smear #
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... Peripheral blood smear ... → Sickle Cell anemia ... malignancy, autoimmune disease ... Microangiopathic hemolytic anemia