22 results
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Ill-appearing, vital sign ... New-onset fever with rash ... #Diagnosis #Dermatology ... #Rash #Maculopapular ... Targetoid #Algorithm #Differential
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... Causes: 1) Exfoliative ... #Diagnosis #Dermatology ... #Rash #Erythroderma ... Nikolsky #Algorithm #Differential
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... WBC >100k, + lab signs ... leukapheresis - TLS prophylaxis ... TLS #diagnosis #management ... #hematology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... - Erosions and crusts ... #dermatology
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin Rash ... - Differential ... Auspitz sign, Koebner's ... #Differential # ... Diagnosis #Algorithm #causes
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... infiltration) Differential ... Liver #Pregnancy #hepatology ... #pathophysiology
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... mass and NO prior signs ... - **MSK rads ... Differential diagnosis ... #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... endothelial damage Prophylaxis ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... Edema in 70% of cases ... Resolution > 15 days Differentials ... DRESS #Syndrome #dermatology ... #diagnosis #management
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... fatigue Heat Rash ... Collapse: • Pathophysiology ... → Syncope • Signs ... #diagnosis #causes