1565 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Amyloid precursor protein ... amyloid precursor protein ... chromosome 21) Signs ... geriatrics #diagnosis #signs
Muehrcke's Lines (Leukonychia striata)
Narrow while transverse lines (Not depressed, compared to Beau's lines). Usually 2 or
states of decreased protein ... synthesis or increase protein ... Clinical #Photo #Sign
Amyloidosis Diagnosis
1) Patient presentation
 • Cardiac-specific signs of amyloidosis: Diastolic heart failure, Heart failure with preserved
Cardiac-specific signs ... • Noncardiac signs ... cardiac-specific signs ... For noncardiac signs ... of monoclonal protein
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Chiari Syndrome - Protein-Losing ... pathophysiology #signs
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Signs of immunodeficiency ... signal transduction protein ... immunoglobulin proteins ... humoral immunity Signs
Diagnostic Testing for Meningitis
History:
 • Triad: Fever, neck stiffness, and altered mental status
 • Sens: 44%
Non-specific Kernig Sign ... 95% Brudzinski Sign ... Glucose, WBC, protein
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
myosin and cardiac proteins ... pathophysiology #diagnosis #signs
Bear Paw Sign of Xanthogranulomatous Pyelonephritis on POCUS

Adult female with right flank pain, fever, leukocytosis, soft
Bear Paw Sign of ... Urine culture-Proteus ... "Bear paw sign." ... Pyelonephritis #BearPaw #Sign
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
significant portal HTN Signs ... HTN: • Ascites protein ... obstruction) • Lack of signs
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Mutations in proteins ... of UMN and LMN signs ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in