33 results
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Syndrome Step ... hematuria and/or proteinuria ... /nephritic syndromes ... dysmorphic RBCs in urine ... #Syndrome #Comparison
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... Nephrotic yndrome—podocyte ... #Nephrotic #Syndromes
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
Syndrome and Nephritic ... Syndrome == Nephrotic ... - Normal/low Proteinuria ... #Syndrome #Nephritic ... #Comparison #Table
Ascites Differential Diagnosis Table - Serum Ascites Albumin Gradient (SAAG)

SAAG ≥ 1.1:
 • Cirrhosis
 • Portal
Diagnosis Table ... - Serum Ascites ... SAAG < 1.1: • Nephrotic ... syndromeMalignancy ... Differential #Diagnosis #Table
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... RBC casts, +/- proteinuria ... anti-phospholipid syndrome ... glomerulopathy, radiation nephritis ... , malignant HTN
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
membrane; GN = glomerulonephritis ... hemolytic-uremic syndrome ... arbitrarily defined as urine ... urine sediment ... #nephrotic #syndrome
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
blood cells on urine ... • Hereditary nephritis ... and >3.5g/day (nephrotic ... range) proteinuria ... • Lupus glomerulonephritis
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary
CLINICAL
 • Nephritic syndrome (Casts)
 • Marked proteinuria (may be
Staphylococcus-associated GlomeruloNephritis ... CLINICAL • Nephritic ... syndrome (Casts ... ) • Marked proteinuria ... (may be nephrotic
Albuminuria (Grades) and Risk for CKD
Normal to mildly increased albuminuria:
 - Albumin excretion rate: < 30
Nephrotic-range ... Urine total protein ... The presence of nephrotic ... is defined as nephrotic ... syndrome
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Budd-Chiari syndrome ... 1.1 g/dL) - Nephrotic ... syndrome - Protein-losing ... - Urine ascites ... HIV-associated peritonitis Malignant