39 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome:
 - Acute poststreptococcal 
glomerulonephritis 
 - Rapidly progressive
Glomerular Diseases ... Nephrotic Syndromes ... Nephritic syndrome ... Nephrotic syndrome ... #Nephrotic #Syndromes
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Syndrome Step ... hematuria and/or proteinuria ... /nephritic syndromes ... the patient have glomerular ... dysmorphic RBCs in urine
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... Nephrotic yndrome—podocyte ... #Nephrotic #Syndromes
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
Syndrome and Nephritic ... Syndrome == Nephrotic ... - Normal/low Proteinuria ... #Syndrome #Nephritic ... #Comparison #Table
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
hemolytic-uremic syndrome ... arbitrarily defined as urine ... urine sediment ... #proteinuria #nephrotic ... #syndrome #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... RBC casts, +/- proteinuria ... formation along glomerular ... anti-phospholipid syndrome ... , malignant HTN
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
blood cells on urine ... • Calculi Glomerular ... • Hereditary nephritis ... and >3.5g/day (nephrotic ... range) proteinuria
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
Rapidly Progressive Glomerulonephritis ... with evidence of glomerular ... disease (hematuria, proteinuria ... nephropathy, lupus nephritis ... staining #Glomerulonephritis
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... disease 24-hour urine ... Serum or urine for ... workup #diagnosis #glomerulonephritis ... #nephrotic #nephritic
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... disease - Alport syndrome ... pain hematuria syndrome ... - Proteinuria ... • Nutcracker syndrome