15 results
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Syndrome Step ... hematuria and/or proteinuria ... /nephritic syndromes ... the patient have glomerular ... dysmorphic RBCs in urine
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... Nephrotic yndrome—podocyte ... #Nephrotic #Syndromes
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
hemolytic-uremic syndrome ... arbitrarily defined as urine ... urine sediment ... #proteinuria #nephrotic ... #syndrome #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... RBC casts, +/- proteinuria ... formation along glomerular ... anti-phospholipid syndrome ... , malignant HTN
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
blood cells on urine ... • Calculi Glomerular ... • Hereditary nephritis ... and >3.5g/day (nephrotic ... range) proteinuria
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... disease 24-hour urine ... Serum or urine for ... workup #diagnosis #glomerulonephritis ... #nephrotic #nephritic
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... disease - Alport syndrome ... pain hematuria syndrome ... - Proteinuria ... • Nutcracker syndrome
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary
CLINICAL
 • Nephritic syndrome (Casts)
 • Marked proteinuria (may be
Staphylococcus-associated GlomeruloNephritis ... CLINICAL • Nephritic ... syndrome (Casts ... ) • Marked proteinuria ... (may be nephrotic
Causes of Hematuria - Differential Diagnosis
Renal:
 - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Diagnosis Renal: - Glomerular ... membrane, Alport syndrome ... , Other glomerulonephritis ... - Interstitial nephritis ... - Physical - Malignancy
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
• Renal: (AKI, proteinuria ... Anti-GBM antibody • Urine ... : UA, Urine protein ... hypercellular glomeruli ... differential #diagnosis #management