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hematology algorithm anemia causes hemolytic classification extravascular atlas evaluation hodgkins key lymphoma management mds monoclonal morphology myelodysplasia myelodysplastic paraproteinemias rbc
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Hemolysis - Differential ... Diagnosis Algorithm ... • MAHA (TTP ... Differential #Diagnosis ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... thrombocytopenic purpura (TTP ... #Hemolytic #Intravascular ... #Causes #differential ... #diagnosis #hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
Algorithm for workup ... TTP/HUS indicates ... thrombocytopenic purpura/hemolytic ... 2012, p 193 #Diagnosis ... #Differential #
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... reflection of intravascular ... WBC count and differential ... impairment #TTP ... #Workup #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... IVIG infusion Intravascular ... Causes: • MAHA: TTP ... #Diagnosis #causes
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... thrombocytopenia - DIC, TTP ... #Anemia #Differential ... #workup #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
thrombocytopenia (ITP ... , Disseminated intravascular ... Morphology #Atlas #key #diagnosis ... #differential # ... hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
PCH • Evans • ITP ... • Coombs (-) hemolytic ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... Hodgkin Lymphoma Workup ... lymph node biopsy (diagnostic ... Immunohistochemical studies (to differentiate ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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