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diagnosis hematology anticoagulation aptt differential ptt cascade causes doac laboratory prolonged testing thrombin warfarin apaxiban apixaban bleeding bruising chemistry clot
Coagulation Cascade - Actions of Anticoagulants • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin • Fondaparinux • Direct
Coagulation Cascade ... - Actions of Anticoagulants ... Warfarin • Direct Thrombin ... Inhibitors: Argatroban, Dabigatran ... #Cascade #Anticoagulants
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Effect of Anticoagulants ... on Coagulation ... Tests PT / INR, ... Clotting Time, Thrombin ... EricsMedicalLectures/ #Anticoagulants
Coagulation cascade and anticoagulants Satyendra Dhar MD, @DharSaty #coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... and anticoagulants ... #coumadin #heparin ... xarelto #DOAC #vWF #thrombin ... #ptt #pt
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
at the site of injury ... #clot #PT #PTT ... anticoagulation #anticoagulant ... #Warfarin #Dabigatran ... Rivaroxaban #Edoxaban #heparin
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/ABNORMAL PTT ... inhibitor and lupus anticoagulant ... syndrome • Lupus anticoagulant ... deficiency • Anticoagulants ... deficiency • Anticoagulant
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
to Evaluate an Abnormal ... Step 1: Is the PT ... Patient Receiving Anticoagulants ... K Antagonists, Heparin ... , or Direct Thrombin
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... unfractionated heparin ... - Other anticoagulants ... drugs e.g. direct thrombin ... Jcortesizaguirr #Abnormal
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... Reduction of pro/anticoagulants ... 100mg/dL) - Heparin
Effect of Direct Oral Anticoagulants on Hemostatic Tests Horizontal bars correspond to the approximate range of detectability
of Direct Oral Anticoagulants ... within and above typical ... concentrations of dabigatran ... assay; ECT = ecarin ... clotting time; TT = thrombin
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
AST/ALT > ALP: Typical ... - If both are normal ... • Albumin • Coagulation ... factors: PT/INR ... replaced by non-hepatic
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