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diagnosis hematology anticoagulation aptt coagulation differential laboratory prolonged apixaban bleeding bruising cascade clot dabigatran dic disseminated doac edoxaban effects evaluation
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
the PT or APTT ... Patient Receiving Anticoagulants ... K Antagonists, Heparin ... , or Direct Thrombin ... Prolonging the PT
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Effect of Anticoagulants ... Coagulation Tests PT ... Clotting Time, Thrombin ... EricsMedicalLectures/ #Anticoagulants ... Anticoagulation #Testing
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... deficiency • Anticoagulant
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... - Other anticoagulants ... drugs e.g. direct thrombin ... #PT #aPTT #Prolonged
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
at the site of injury ... Thrombin, then primes ... #clot #PT #PTT ... anticoagulation #anticoagulant ... Rivaroxaban #Edoxaban #heparin
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... /PTT • Low plasma ... • Increased thrombin ... Fibrinogen: ↓ • PT ... Reduction of pro/anticoagulants
Effect of Direct Oral Anticoagulants on Hemostatic Tests Horizontal bars correspond to the approximate range of detectability
of Direct Oral Anticoagulants ... within and above typical ... = thrombin time ... hematology #laboratory #testing ... #aptt
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