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hematology clinical differential pathophysiology causes management pocus laboratory abnormal algorithm aptt echocardiogram embolism intransit prolonged ultrasound cascade clots dic disseminated
Coagulation cascade and anticoagulants Satyendra Dhar MD, @DharSaty #coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... @DharSaty #coagulation ... xarelto #DOAC #vWF #thrombin ... #ptt #pt
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation ... platelet aggregation PT ... consumption of coagulation ... using INR use PT ... ISTH #Scoring #diagnosis
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... and endothelial cells ... #Coagulation #Cascade ... #clot #PT #PTT ... #diagnosis #models
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Investigation of Abnormal Coagulation ... Tests - Prolonged PT ... and Prolonged PT ... #Algorithm #Coagulation ... Laboratory #Hematology #Diagnosis
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Anticoagulants on Coagulation ... Tests PT / INR, ... Clotting Time, Thrombin ... Anticoagulation #Testing #Diagnosis
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged PT ... • Prolonged PT ... • Prolonged PT ... #Differential #Diagnosis ... Causes #Hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... Schistocytes, helmet cells ... #diagnosis #causes
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Congenital intrinsic coagulation ... drugs e.g. direct thrombin ... intravascular coagulation ... Prolonged #Causes #diagnosis ... differential #hematology #coagulation
Coagulation Cascade Mnemonic - PITT vs PET PITT (with an I) = Intrinsic = APTT
Coagulation Cascade ... E)= Extrinsic=PT ... @pinoygastro #Coagulation ... Mnemonic #PITT #PET #diagnosis
Pulmonary Embolism with IVC Thrombus In Transit A patient presents with chest pain. Which of the following
Embolism with IVC Thrombus ... most support her diagnosis ... demonstrate an IVC thrombus ... Embolism #IVC #Thrombus ... echocardiogram #a4c
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