4 results
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#clot #PT #PTT ... diagnosis #models #hematology ... #inhibitor #Apixaban ... #Rivaroxaban #Edoxaban ... #heparin #pathway
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
Pt had extensive ... Started on heparin ... later with normal LV ... Echocardiogram #A4C ... #Clots #InTransit
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
- Rivaroxaban, apixaban ... , edoxaban (typically ... unfractionated heparin ... drugs e.g. direct thrombin ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... significant fibrin clot ... treatment #management #hematology