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coagulation diagnosis causes abnormal anticoagulant anticoagulation apixaban aptt cascade clinical clots dabigatran dic differential echocardiogram inhibitor intransit intravascular management mcconnells
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
and endothelial cells ... #clot #PT #PTT ... diagnosis #models #hematology ... #Rivaroxaban #Edoxaban ... #heparin #pathway
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
Pt had extensive ... Started on heparin ... later with normal LV ... Echocardiogram #A4C ... #Clots #InTransit
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 Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... • Prolonged PT ... • Increased thrombin ... significant fibrin clot ... treatment #management #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Rivaroxaban, apixaban, edoxaban ... unfractionated heparin ... drugs e.g. direct thrombin ... Disseminated intravascular ... #differential #hematology
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