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coagulation causes abnormal anticoagulant anticoagulation apixaban aptt cascade clinical clot clots dabigatran dic differential disseminated echocardiogram heparin inhibitor intransit intravascular
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
and endothelial cells ... #clot #PT #PTT ... #diagnosis #models ... #hematology #pathophysiology ... #Rivaroxaban #Edoxaban
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
What's the diagnosis ... Thrombus in transit ... Pt had extensive ... later with normal LV ... Echocardiogram #A4C
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 Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal PT ... Rivaroxaban, apixaban, edoxaban ... drugs e.g. direct thrombin ... Prolonged #Causes #diagnosis ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... #Coagulation #diagnosis ... treatment #management #hematology
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