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diagnosis hematology abnormal intravascular prolonged algorithm bleeding bruising hemorrhage hemostasis isth laboratory management obgyn obstetrics postpartum pph scoring treatment
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Scoring System for Disseminated ... (DIC) Platelet ... , aPTT: • Expected ... using INR use PT ... #Disseminated #
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Coagulation (DIC ... • Prolonged PT ... • Increased thrombin ... #Disseminated #
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and the aPTT ... drugs (e.g. direct thrombin ... hemorrhage • Disseminated ... intravascularcoagulation (DIC ... hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... drugs e.g. direct thrombin ... Disseminated intravascular ... coagulation (DIC ... #differential #
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... inhibitor of a coagulation ... failure, disseminated ... discern these causes ... warfarin, direct thrombin
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... Hemorrhage - Differential ... or percreta) Thrombin ... HELLP syndrome • Disseminated ... (DIC) • Anti-coagulation
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