4 results
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
along with FXIIa (intrinsic ... #clot #PT #PTT ... #diagnosis #models ... anticoagulation #anticoagulant ... #inhibitor #Apixaban
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
What's the diagnosis ... Thrombus in transit ... Pt had extensive ... Echocardiogram #A4C ... #Clots #InTransit
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
- Rivaroxaban, apixaban ... heparin - Other anticoagulants ... Congenital intrinsic ... drugs e.g. direct thrombin ... Prolonged #Causes #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... • Increased thrombin ... significant fibrin clot ... Reduction of pro/anticoagulants ... #diagnosis #causes