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diagnosis management dic disseminated intravascular product reactions anticoagulant anticoagulation apixaban cascade causes chemistry clot dabigatran differential edoxaban heparin hepatology inhibitor
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation ... platelet aggregation PT ... using INR use PT ... acute-phase reactant Blood ... Scoring #diagnosis #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... and endothelial cells ... #Coagulation #Cascade ... #clot #PT #PTT ... diagnosis #models #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... • Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... treatment #management #hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
• Albumin • Coagulation ... factors: PT/INR ... intestines, White blood ... cells Unconjugated ... #differential #Hepatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... screen - determines blood ... potassium from lysed cells ... RBCs (stored at 4C ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... the banked donor blood ... potassium from lysed cells ... RBCs (stored at 4C ... diagnosis #management #hematology
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