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diagnosis differential management abnormal aptt blood cardiology clinical echocardiogram pocus product prolonged reactions anticoagulant anticoagulation apixaban bleeding bruising cardiac cascade
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... and endothelial cells ... #Coagulation #Cascade ... #clot #PT #PTT ... diagnosis #models #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... drugs e.g. direct thrombin ... #differential #hematology ... #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... #diagnosis #causes ... treatment #management #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the PT ... drugs (e.g. direct thrombin ... #differential #hematology ... #coagulation
Constrictive Pericarditis on POCUS Echocardiogram - Subcostal View Young Lupus patient admitted to hospital new onset HFpEF.
could pinpoint the cause ... Also has pericardial ... effusion/pericardial ... one month ago-pt ... clinical #cardiology #s4C
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 Complex Pericardial Effusion with Tamponade on POCUS Echocardiogram - A4C Pt sent to ED c intradialytic hypotension.
Echocardiogram - A4C ... Pt sent to ED c ... Pt has large pericardial ... consider serious causes ... Echocardiogram #A4C
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 Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... intravascular coagulation ... discern these causes ... warfarin, direct thrombin ... Differential #Diagnosis #Hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... potassium from lysed cells ... RBCs (stored at 4C ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... potassium from lysed cells ... RBCs (stored at 4C ... diagnosis #management #hematology
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