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diagnosis hematology anticoagulant apixaban cascade causes clinical clot clots dabigatran dic disseminated echocardiogram edoxaban inhibitor intransit intravascular management models pathophysiology
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
Thrombus in transit ... Pt had extensive ... Started on heparin ... Echocardiogram #A4C ... #McConnells #Sign
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 The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... #platelet #thrombin ... #clot #PT #PTT ... pathophysiology #anticoagulation ... Rivaroxaban #Edoxaban #heparin
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... • Increased thrombin ... Findings in DIC: • Platelet ... Fibrinogen: ↓ • PT ... Thrombocytopenia - Platelet
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