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hematology coagulation causes differential clots echocardiogram mcconnells pocus prolonged sign anticoagulant apixaban bleeding bruising cascade clot dabigatran dic disseminated edoxaban
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
What's the diagnosis ... Thrombus in transit ... Pt had extensive ... #Clinical #POCUS ... Echocardiogram #A4C
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 Cool echo - RV strain, McConnell sign, and CLOT IN TRANSIT!! BP is normal and pt
BP is normal and ... pt not in distress ... @eabramsMD #Clinical ... Echocardiogram #A4C ... Pulmonary #Embolism #Thrombus
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 Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... Congenital intrinsic ... drugs e.g. direct thrombin ... #PT #aPTT #Prolonged ... #Causes #diagnosis
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and the aPTT ... affected in the intrinsic ... drugs (e.g. direct thrombin ... amyloidosis #Abnormal ... #PT #aPTT #Prolonged
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... warfarin, direct thrombin
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
along with FXIIa (intrinsic ... Thrombin, then primes ... #clot #PT #PTT ... #diagnosis #models ... pathophysiology #anticoagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... • Increased thrombin ... organ damage Clinical ... INR < 2.3 - APTT ... #Coagulation #diagnosis
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