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coagulation causes differential abnormal dic disseminated prolonged anticoagulant anticoagulation bleeding bruising cascade clot dabigatran edoxaban hemostasis heparin inhibitor isth laboratory
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
- Rivaroxaban, apixaban ... Congenital intrinsic ... drugs e.g. direct thrombin ... #Causes #diagnosis ... #differential #hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
for Disseminated Intravascular ... , aPTT: • Expected ... using INR use PT ... ISTH #Scoring #diagnosis ... #hematology #laboratory
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
along with FXIIa (intrinsic ... #clot #PT #PTT ... #diagnosis #models ... #hematology #pathophysiology ... #inhibitor #Apixaban
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... PT and the aPTT ... affected in the intrinsic ... drugs (e.g. direct thrombin ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... • Prolonged PT ... • Increased thrombin ... #Coagulation #diagnosis ... treatment #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... , disseminated intravascular ... pathway to the intrinsic ... warfarin, direct thrombin ... #Hematology
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