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coagulation causes dic differential disseminated abnormal anticoagulant anticoagulation bleeding bruising cascade dabigatran edoxaban hemostasis heparin inhibitor isth laboratory management models
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
, aPTT: • Expected ... using INR use PT ... to form clots, ... ISTH #Scoring #diagnosis ... #hematology #laboratory
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
along with FXIIa (intrinsic ... #clot #PT #PTT ... #diagnosis #models ... #hematology #pathophysiology ... #inhibitor #Apixaban
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
- Rivaroxaban, apixaban ... Congenital intrinsic ... drugs e.g. direct thrombin ... #Causes #diagnosis ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... • Increased thrombin ... significant fibrin clot ... #Coagulation #diagnosis ... treatment #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... , disseminated intravascular ... pathway to the intrinsic ... warfarin, direct thrombin ... #Hematology
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