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hematology coagulation anticoagulation causes differential abnormal anticoagulant aptt bleeding bruising cascade clot dabigatran disseminated edoxaban effects hemostasis hepatic hepatology inhibitor
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Coagulation Tests PT ... Clotting Time, Thrombin ... Rivaroxaban Apixaban ... Anticoagulation #Testing ... #Diagnosis #Laboratory
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Increased thrombin ... venipuncture sites Laboratory ... significant fibrin clot ... Reduction of pro/anticoagulants ... #Coagulation #diagnosis
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#clot #PT #PTT ... #diagnosis #models ... anticoagulation #anticoagulant ... #inhibitor #Apixaban ... Rivaroxaban #Edoxaban #heparin
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
- Rivaroxaban, apixaban ... - Other anticoagulants ... drugs e.g. direct thrombin ... intravascular coagulation (DIC ... Prolonged #Causes #diagnosis
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... Findings in Hepatic ... - Prolonged PT ... As a result of DIC ... #Diagnosis #Testing
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... Acquired: • Heparin ... fibrinogen levels, and testing ... disease • Acute DIC ... warfarin, direct thrombin
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