10 results
Mean Arterial Pressure (MAP)

Average arterial pressure throughout one cardiac cycle, systole, and diastole. 
Surrogate indicator of
affected by the chronotropy ... afterload #Heartrate #chronotropy ... dromotropy #lusitropy #Pulsepressure
Calcium Channel Blockers - Dihydropyridines vs Non-Dihydropyridines
Dihydropyridines (amlodipine, felodipine, nifedipine, nicardipine)
 • SVR: Decrease
 • Inotropy:
: No effect • Chronotropy ... Inotropy: Decrease • Chronotropy
Clinician's Pocket Guide to Vasopressors - Receptor Profiles and Hemodynamic Parameters
 • Systemic Vascular Resistance -
contractions • Chornotropy
Mean arterial pressure (MAP)

A common method used to estimate the MAP is the following formula:
* MAP
meanarterialpressure #pulsepressure
Recurrent Polymorphic VT/Torsades de Pointes - Management Algorithm
Drugs that prolong QT interval:
 • Class 1a (quinidine,
minutes Increasing chronotropy
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
not inotropic/chronotropic
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
• Heart - ↑ Chronotropy
Pacemaker Indications
Class I
 • Symptomatic sinus node dysfunction
 • 3° AV or type 2 2° AV
• Symptomatic chronotropic
Guideline-Directed Medical Therapy (GDMT) in HFrEF and CKD

 • Class I pillars of HFrEF GDMT across
sGC stimulator, Chronotropes
Arterial Line - Pulse Pressure Variation (PPV)
Pressure Variation (PPV) represents an interaction between lungs and heart.
#artline #PPV #pulsepressure