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Causes of Purpura - Differential Diagnosis Non-PalpabIe → Palpable • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura ... Diagnosis Non-PalpabIe ... → Palpable • ... BrighamChiefs #Purpura ... #Causes #Differential
Causes of Purpura - Differential Diagnosis Disruption in Vascular Integrity: • Trauma, Infection, Vasculitis, Drug induced
Causes of Purpura ... C), Pigmented purpuric ... BrighamChiefs #Purpura ... #nonpalpable #palpable ... #Causes #Differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... OF NON-PALPABLE ... • Secondary Causes ... OF PALPABLE PURPURA ... #rheumatology #palpable
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Toxic Patient: • Palpable ... Henoch Schonlein Purpura ... Rash: - Purpura ... Diagnosis #Algorithm #Causes
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... • Petechiae, Palpable ... purpura (16%) ... • Petechiae • Palpable ... overlying purpuric
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
capillaritis, palpable ... tract, and often causes ... deposits skin) • Palpable ... (red macules, palpable ... Vasculitis) • Palpable
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
thrombocytopenic purpura ... cell/white cell casts ... skin (alopecia, purpura ... , palpable purpura ... Nephrocalcinosis causes
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
Viral replication causes ... endothelial cells - Palpable ... or necrotic purpura
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
areas of the body Purpura ... Purpura due to vasculitis ... is usually palpable ... Wet purpura is the ... ecchymosis) is caused
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Arthralgia - Purpura ... Cryoglobulins Cause ... Clinical triad of Palpable ... purpura, Arthralgia
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