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differential vasculitis behcet cryoglobulinemia cryoglobulins dermatology disease disorders eosinophil eosinophilia erythematosus hematology lupus management nonpalpable pan pathophysiology petechiae petechial polyarteritisnodosa
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
Petechial/Purpuric ... ) purpura occurs ... Nonpalpable purpura ... require emergent evaluation ... #Purpuric #Rash
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
Algorithm for workup ... thrombocytopenic purpura ... thrombocytopenia, Hematology ... 2012, p 193 #Diagnosis ... Thrombocytopenia #Evaluation
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis: • Purpura ... purpura: Strong ... purpura • Pauci ... purpura, joint ... purpura (lower
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
endothelial cells - Palpable ... or necrotic purpura ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis: • Purpura ... Henoch Schonlein Purpura ... erythematous nodules, purpura ... purpura: strong ... purpura.
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... during medical evaluation ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
rash, Vasculitis, Purpura ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... Clinical triad of Palpable ... purpura, Arthralgia ... Henoch-Schönlein purpura ... #rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
multiforme-like lesions, palpable ... purpura, Pathergy ... meningitis), MCC CNS symptoms ... #management #signs ... #symptoms #rheumatology
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