474 results
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
endothelial cells - Palpable ... or necrotic purpura ... Pathophysiology #Diagnosis #Signs ... #Symptoms #Vasculitis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... sign of cutaneous ... • Progressive symptoms ... capillaritis, palpable ... (red macules, palpable
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis: • Purpura ... Presentation - Systemic Symptoms ... scleritis • Palpable ... sign of cutaneous ... Skin -> causing palpable
Algorithm for Diagnosis of the Petechial / Purpuric Rash

Febrile/Toxic, Palpable: 
 - Meningococcaemia, Disseminated Gonococcal Infection,
the Petechial / Purpuric ... Febrile/Toxic, Palpable ... Febrile/Toxic, Non-palpable ... Afebrile/Non-Toxic, Palpable ... Non-Toxic, Non-palpable
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
multiforme-like lesions, palpable ... purpura, Pathergy ... meningitis), MCC CNS symptoms ... diagnosis #management #signs ... #symptoms #rheumatology
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
Petechial/Purpuric ... the etiology of palpable ... Palpable (raised ... the lesions are palpable ... patients with palpable
An Approach to the Unknown Rash: Petechial-Purpuric Rash 
#Diagnosis #Dermatology #Petechial #Purpura #Purpuric #Rash #Palpable #Algorithm
Rash: Petechial-Purpuric ... Dermatology #Petechial #Purpura ... #Purpuric #Rash ... #Palpable #Algorithm
Palpable Purpura - Rash Algorithm
#Diagnosis #Dermatology #Rash #Palpable #Purpura #Differential #Algorithm
Palpable Purpura ... Dermatology #Rash #Palpable ... #Purpura #Differential
Causes of Purpura - Differential Diagnosis
Non-PalpabIe → Palpable
 • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura ... Diagnosis Non-PalpabIe ... → Palpable • ... BrighamChiefs #Purpura ... #nonpalpable #palpable
Clinical Manifestations of Henoch Schonlein Purpura

#Diagnosis #Henoch #Schonlein #Purpura #Signs #Symptoms
Henoch Schonlein Purpura ... Henoch #Schonlein #Purpura ... #Signs #Symptoms