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diagnosis rheumatology differential causes msk algorithm cppd management orthopedics testing activetb aortic approach bone calcium cardiology classification comparison cryoglobulinemia cryoglobulins
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
with passive AND active ... necrosis, Lyme disease ... Workup: arthrocentesis ... w/ fluid culture ... in sexually active
Causes of Severe Aortic Regurgitation - Differential Diagnosis Acute: • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
Leaflet: Traumatic Rupture ... Fever, Whipple Disease ... , Crohn Disease ... Polychondritis, Reactive ... Disease, Cogan's
Tuberculosis Testing LATENT TB • LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
intermediate risk of disease ... TB AFB smear microscopy ... Mycobacterial culture ... Mycobacterial culture ... Testing #Diagnosis #Workup
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
Early Rheumatic Disease ... • Rheumatoid Arthritis ... polyangiitis (GPA)/microscopic ... Asymmetric (Psoriatic Arthritis ... • Psoriatic Arthritis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Gram stain and culture ... polarized light microscopy ... Polyarthritis: • Blood cultures ... #laboratory #workup
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
), RA, crystal disease ... gonococcal, Lyme), reactive ... for cell count, culture ... Inflammatory, crystalline disease ... rheumatology #approach #workup
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... deposit and can activate ... • Gram stain, culture ... Gram stain and culture ... acute gout • ↑ C-reactive
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can activate ... • Autoimmune diseases ... arthralgia, and arthritis ... vasculitis - GPA, EGPA, microscopic ... SLE), rheumatoid arthritis
Bone Deformity / Limp - Differential Diagnosis Algorithm Infection • Septic Arthritis • Cortical Hypertrophy •
Synovitis • Reactive ... Arthritis Other ... Legg-Calve-Perthes Disease ... Osgood-Schlatter Disease ... (e.g., Tendon Rupture
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate Deposition Disease ... deposit and can activate ... • Underlying disease ... • Gram stain, culture ... monoarticular CPPD disease
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