56 results
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
calcification of both adrenal ... confirmed the diagnosis ... and gut, which causes ... #clincial #peds ... #infant #NEJM #
Decompression Sickness - The physical examination revealed diffuse violaceous skin mottling over his trunk and arms
extent of the nausea ... #Clinical #Derm ... #EM #Radiology # ... Pneumatosis #CT #NEJM
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... with or without treatment ... , but without treatment ... resembling rashes caused ... #Diagnosis #Clinical
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary
CLINICAL
 • Nephritic syndrome (Casts)
 • Marked proteinuria (may be
GlomeruloNephritis - Diagnosis ... Management Summary CLINICAL ... Nephritic syndrome (Casts ... • Vasculitic rash ... deposits common TREATMENT
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... arthritis, Skin rash ... Differential Diaqnoses ... Coxsackie, CMV, EBV ... #management #treatment
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... osmolarity If cause ... investigations depending on clinical ... ANCA, ANA, Anti-GBM ... #nephrology #causes
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause ... Treatment: • ... #management #treatment
Macroglossia in Light-Chain Amyloidosis- Physical examination revealed macroglossia, with indentations from the teeth (Panel A)...A biopsy
well-recognized cause ... Early diagnosis ... and treatment are ... #amyloidosis #clinical ... AL #lightchain #NEJM
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... #rheumatology #diagnosis
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Hematologic disease caused ... Lutzomyia verrucarum Clinical ... toxo reactivation Clinical ... Chronic phase: Derm ... TREATMENT: ​• Acute