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management hematology classification vasculitis adultonset antinxp2 antinxp2dm arteritis autoimmune clinical dermatology dermatomyositis disease encephalopathy gap gca giantcell globulin hodgkins lichen
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... fraction < 20% Differential ... Coxsackie, CMV, EBV ... #management #treatment ... #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
coagulopathy) • CBC w differential ... antibody, Anti-GBM ... Goodpasture's cause ... #Syndromes #differential ... #treatment
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... in literature (NEJM ... (Cornelia NEJM ... Treatment of GCA ... them, but urgent rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... Diagnosis Framework ... tract, and often causes ... mucositis - Rash ... #diagnosis #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Reversible course Differential ... epilepticus Treatment ... the underlying cause ... • Treatment of ... until cause identified
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... Diagnosis Neonate ... hypertension and/or drug treatment ... #diagnosis #causes ... #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... pulmonary and renal ... , mucositis • Rash ... tract, and often causes ... #Diagnosis #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... lymph node biopsy (diagnostic ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... Hodgkins #lymphoma #diagnosis
Lichen Planus- ...On examination, numerous purple papules were noted on the anterior surface of the forearms
sawtooth rete pegs ... confirming the diagnosis ... used in primary treatment ... #NEJM #clinical ... lichen #planus #derm
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Causes of Monoclonal ... acute HIV, HBV, EBV ... cancers, HCC, renal ... Gap #ProteinGap #differential ... #diagnosis #hematology
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