11 results
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... Viral: HIV, HCV, EBV ... : ITP, HITT - Autoimmune ... : SLE, RA, antiphospholipid ... #hematology
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... myopathy - Autoimmune ... tissue disorder, SLE ... #Elevated #CK #differential ... #diagnosis #rhabdomyolysis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... solid cancers • Autoimmune ... diseases: SLE++ ... treatment #summary #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... disease • Non-autoimmune ... rheumatologic diseases ... #Rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis is an autoimmune ... Hodgkin lymphoma - Autoimmune ... rheumatoid arthritis, SLE ... life-threatening Differential ... myasthenia Diagnosis
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
W/ LOW CD4 • Autoimmune ... (Sjogren, SLE, ... EBV. CMV. ... #hematology #Differential ... #Causes #lymphocytopenia
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Diagnosis Framework ... tract, and often causes ... mucositis - Rash ... vasculitis, and SLE ... #diagnosis #rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Immunosuppression • Autoimmune ... Hodgkin Lymphoma - Clinical ... lymph node biopsy (diagnostic ... Immunohistochemical studies (to differentiate
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... diseases, such as SLE ... , mucositis • Rash ... tract, and often causes ... #Diagnosis #Rheumatology
Lichen Planus- ...On examination, numerous purple papules were noted on the anterior surface of the forearms
confirming the diagnosis ... Although the cause ... thought to be an autoimmune ... #NEJM #clinical ... #photo #lichen #