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diagnosis oncology rheumatology dermatology differential erythematosus sle systemic aplastic cellulitis classification gap globulin hiv infection legs leukemia management photo protein
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... ) Blood (75%): Anemia
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Classification: • Acute ... Clinical Features ... lymphopenia, low PLT • Anemia
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
Vibrio Vulnificus skin ... marine microbiota & causes ... hemochromatosis, hemolytic anemia ... immunosuppressive meds ... #legs #clinical
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... - Rash: multiple ... Causes: - Idiopathic ... , breast CA - Hematologic ... - Lupus - Leukemia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Clinical Presentation ... Headaches • Pale skin ... and petechiae Causes ... #oncology #hematology
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Syndrome Acute ... sweats (28%) • Skin ... rash (48%) • ... enzymes ↑ • Mild anemia ... Epstein-Barr virus (EBV
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... glomerulonephritis) • Anti-GBM ... inflammation Others: • Lupus ... mucositis - Rash ... such as systemic lupus
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... - infiltrates (anemia ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
gammopathy, and skin ... changes (POEMS syndrome ... HIV, HBV, EBV, ... Thalassemia, Sickle cell anemia ... inflammation (acute
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