24 results
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... - Differential Diagnosis ... Emboli, Thrombosis, Vasculitis ... GN: ANCA, Anti-GBM ... #nephrology #causes
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... • Limited to Kidney ... involvement: Anti-GBM ... Glomerulonephritis #Vasculitis ... #differential #diagnosis
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... - Small vessel vasculitis ... tubular necrosis (causes ... : sepsis, meds, ... Classification #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... tract, and often causes ... Polyarteritis Nodosa: - Kidneys ... mucositis - Rash ... Kidneys -> glomerulonephritis
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Infectious: Influenza, EBV ... Bacteremia, Sepsis • Kidneys ... Rhabdomyolysis, Critical ... PMR, RA, SLE, Vasculitis ... #causes #neurology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... and Differential Diagnosis ... investigations depending on clinical ... Glomerulonephritis / Vasculits ... ANCA, ANA, Anti-GBM
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Maculopapular rash ... Differential Diagnosis ... #dermatology #rash
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
fires, heating pads ... Haverhill fever caused ... Rash is usually ... of necrotizing vasculitis ... #differential #diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... musculoskeletal systems • Kidneys ... , mucositis • Rash ... tract, and often causes ... pain and GN Anti-GBM
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
confirmed the diagnosis ... acid lipase is critical ... and gut, which causes ... #clincial #peds ... calcifications #infant #NEJM