12 results
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... - Differential Diagnosis ... Emboli, Thrombosis, Vasculitis ... GN: ANCA, Anti-GBM ... #nephrology #causes
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... • Limited to Kidney ... involvement: Anti-GBM ... Glomerulonephritis #Vasculitis ... #differential #diagnosis
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... - Small vessel vasculitis ... tubular necrosis (causes ... : sepsis, meds, ... Classification #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... tract, and often causes ... Polyarteritis Nodosa: - Kidneys ... mucositis - Rash ... Kidneys -> glomerulonephritis
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
- Differential Diagnosis ... Infectious: Influenza, EBV ... Bacteremia, Sepsis • Kidneys ... PMR, RA, SLE, Vasculitis ... #causes #neurology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... and Differential Diagnosis ... osmolarity If cause ... Glomerulonephritis / Vasculits ... ANCA, ANA, Anti-GBM
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... Skin involvement, Kidney ... for alternative causes ... HBV, HCV, HEV, EBV ... hepatitis #DILI #DrugInduced
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
myalgia, serositis, Kidney ... NPSLE rare, Malar rash ... Manifestations: Malar rash ... Lupusreference #druginduced ... #rheumatology #diagnosis
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
fires, heating pads ... Haverhill fever caused ... Rash is usually ... of necrotizing vasculitis ... #differential #diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... musculoskeletal systems • Kidneys ... , mucositis • Rash ... tract, and often causes ... pain and GN Anti-GBM