9 results
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Emboli, Thrombosis, Vasculitis ... GN: ANCA, Anti-GBM ... #AKI #Acute #Kidney ... Diagnosis #nephrology #causes
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... - Small vessel vasculitis ... tubular necrosis (causes ... : sepsis, meds, ... #AKI #Acute #Kidney
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... • Limited to Kidney ... involvement: Anti-GBM ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... osmolarity If cause ... Glomerulonephritis / Vasculits ... ANCA, ANA, Anti-GBM ... #Injury #AKI #Workup
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Polyarteritis Nodosa: - Kidneys ... mucositis - Rash ... Kidneys -> glomerulonephritis ... differential #diagnosis #rheumatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... HBV, HCV, HEV, EBV ... disease: > 2 • NASH ... cardiac muscle, RBC, kidney ... cardiac muscle, kidneys
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
musculoskeletal systems • Kidneys ... , mucositis • Rash ... tract, and often causes ... pain and GN Anti-GBM ... Differential #Diagnosis #Rheumatology
Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis - Kupperman et al. NEJM 2018

https://www.nejm.org/doi/full/10.1056/NEJMoa1716816
Study
NEJM 2018 https ... of brain injury ... brain injury in ... TessaRDavis #EBM ... VisualAbstract #Peds
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Crisis: 1) Acute kidney ... injury 2) Abrupt ... , add other BP meds ... • Refractory cases ... Renal #Crisis #rheumatology