10 results
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
abdomen revealed calcification ... and gut, which causes ... #clincial #peds ... #adrenal #calcifications ... #infant #NEJM #
Infographic depicting the main pearls of various types of congenital adrenal hyperplasia for the medical student.
CAH #algorithm #causes ... #pediatrics #CongenitalAdrenalHyperplasia ... comparison #treatment #Peds ... Endocrinology #Adrenal #pathophysiology
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
#Pathophysiology ... #GI #IM #NASH # ... NonAlcoholicFattyLiverDisease #NEJM
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
& hemorrhagic rash ... Vesicular & pruritic rash ... > Inflammation causes ... #Immunization #peds ... #pediatrics #pathophysiology
Hemolysis in Hereditary Spherocytosis. Panel A shows the structure of a normal red cell and a
deficiencies that cause ... #Pathophysiology ... #Honc #IM #Spherocytosis ... HereditarySpherocytosis #NEJM
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Passive neck flexion causes ... While the pathophysiology ... #PhysicalExam #Pediatrics ... #Peds
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Alkaptonuria (Black Urine Disease)
Urine turns dark when left standing due to oxidation of homogentisic acid 
Clinical
deposits) • Calcification ... Alkaptonuria #BlackUrine #Peds ... #Pediatrics #Diagnosis ... #Pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds ... #pediatrics
Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis - Kupperman et al. NEJM 2018

https://www.nejm.org/doi/full/10.1056/NEJMoa1716816
Study
Infusion Rates for Pediatric ... NEJM 2018 https ... VisualAbstract #Peds ... #Pediatrics #DKA ... Infusion #Rates #NEJM
Fetal and Post Transition Circulation

In the fetal circulatory system, oxygenated blood is delivered via the umbilical
oxygenated blood passes ... #Circulation #Pathophysiology ... Cardiology #Anatomy #Peds ... #Pediatrics