14 results
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... death Common Clinical ... anaphylaxis, toxins/meds ... diagnosis #management #Overview ... #differential #causes
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
rigors, diarrhea, nausea ... in multipressor shock ... critical illness ... Final dx: Septic shock ... #clinical #photo
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... death Common Clinical ... anaphylaxis, toxins/meds ... diagnosis #management #Overview ... #differential #causes
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
calcification of both adrenal ... acid lipase is critical ... gut, which causes ... #clincial #peds ... #infant #NEJM #
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
: Pathogenesis and ... Clinical Findings ... enzyme 21-OHase causes ... vomiting • Late (shock ... endocrinology #peds
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dogs & latter can cause ... gram-negative bacillus cause ... endocarditis, sepsis, shock ... #dermatology #clinical ... #photo
Moccasin-variety Tinea Pedis 
70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Over the years: rash ... dermatophytes cause ... pitted keratolysis; and ... Variety #type #clinical ... #photo #foot #dermatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Coagulation (DIC) Overview ... organ damage Clinical ... Bleeding (64%) • Renal ... dysfunction (16%) • Shock ... Treat primary cause
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Syndrome (PRES) Overview ... Infection/Sepsis/Shock ... the underlying cause ... Seizures: Treat with AEDs ... until cause identified
Capnocytophaga
GNR with long fusiform shape.  Fastidious facultative anaerobe that grows slowly and needs enriched agar
C.
= most common cause ... cats) Classic clinical ... scenario: septic shock ... with fever, rash ... , hypotension, renal