41 results
diagnosis rheumatology dermatology lupus disease nephrology neurology sle erythematosus hemophagocytic hlh lymphohistiocytosis systemic cardiology druginduced hepatology oncology pharmacology signs summary
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Clinical Presentation ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... #Management #Hematology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... : • Treatment: ... Behcets #disease #Syndrome ... #Treatment #management ... #pharmacology #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... accumulation of clinical ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases ... life-threatening • Treatment ... #Summary #rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
extensive skin rash ... Edema in 70% of cases ... Resolution > 15 days Differentials ... disease: symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... arthritis, Skin rash ... fraction < 20% Differential ... Disease #diagnosis #management ... #treatment #rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Clinical Picture ... life-threatening Differential ... Clinical DX: - ... immunosuppressants - Meds ... Gravis #diagnosis #management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Treatment depends ... maintained fever CAUSES ... #Hyperthermia #Differential ... Checklist #Diagnosis #Management
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
carotid sinus syndrome ... syncope (ruling out differential ... further guide management ... should be guided by clinical ... The treatment strategy
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Discontinuation of causal ... 40, F:M 9:1 • Clinical ... #diagnosis #management
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