23 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... reticularis Differential ... vasculitis (inflamed blood ... #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... plateletcount), peripheral blood ... PT, aPTT(liver disease ... bypass), LFT (liver disease ... #Workup #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Volume (MCV) - Differential ... Algorithm Normal Blood ... • Liver Disease ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... Diagnosis Algorithm Blood ... Anemia of Chronic Disease ... Diagnosis #Algorithm #Causes ... #Hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... the total white blood ... Colitis and Crohn’s Disease ... #Diagnosis #causes ... #hematology #basophils
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
chronic kidney disease ... , Acute blood loss ... morphologic #mcv #differential ... #diagnosis #causes ... #hematology
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
fires, heating pads ... early localized disease ... called "Bazin's disease ... comparison #table #differential ... #diagnosis #dermatology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... normal in mild cases ... Avoid meds that ... #treatment #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... Edema in 70% of cases ... Resolution > 15 days Differentials ... DRESS #Syndrome #dermatology ... #diagnosis #management
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... onset [33-74%] • Blood ... severity of the disease ... Dermatomyositis #rheumatology ... #dermatology #diagnosis