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diagnosis hematology rheumatology syndrome blood oncology reactions sle activation antinxp2 antinxp2dm cardiology cardiomyopathy classification comparison dermatomyositis dress druginduced erythematosus hemophilia
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Manifestations: Malar rash ... life-threatening • Treatment ... Usual therapeutic management ... Evolution: Chronic disease
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... Petechial or purpuric rash ... Fibrin degradation products ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... normal in mild cases ... Avoid meds that ... #treatment #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
extensive skin rash ... Edema in 70% of cases ... : symptomatic treatment ... • Severe disease ... DRESS #Syndrome #dermatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
maculopapular rash ... Causes purpura & ... TRALI): Leading cause ... Transfusions #diagnosis #management ... #hematology #reactions
Syphilis - Clinical Manifestations and Treatment 1) Primary Syphilis • Direct lesion contact during sex is responsible
responsible for most cases ... → Ulcerates to produce ... loss • Skin: Rash ... meningovascular disease ... stages #diagnosis #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Causes purpura & ... TRALI): Leading cause ... Transfusion #diagnosis #management ... #hematology #reactions
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Causes: - Idiopathic ... ’s syndrome - Lupus ... Treatment: - Systemic ... Syndrome #diagnosis #dermatology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Valvular heart disease ... Avoid estrogen products ... teratogenic GDMT meds ... #cardiology #treatment
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