8 results
diagnosis lupus summary activation antinxp2 antinxp2dm aosd comparison dermatology dermatomyositis druginduced erythematosus hematology hemophagocytic hlh lymphohistiocytosis macrophage mas polychondritis relapsing
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... Prunelle Getten #AdultOnset ... #Stills #Disease ... #diagnosis #management ... #treatment #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
maculopapular rash ... BrighamChiefs #AdultOnset ... #Stills #Disease ... #AOSD #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Manifestations: Malar rash ... Positive in 60-80% of cases ... life-threatening • Treatment ... : Chronic disease ... #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Manifestations: Malar rash ... : Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
: SLE+++, Adult-onset ... Still disease, ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Adult-onset Still ... Petechial or purpuric rash ... erythematosus [SLE ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
as: • SLE • RA ... Polyarteritis Nodosa, GCA ... affected tissue Treatment ... Polychondritis #rheumatology ... #diagnosis #management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
But can still have ... Muscle atrophy may cause ... had more severe disease ... positive patients Treatment ... #rheumatology #
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